Risham Singh Ghalot, Lyubomir Lazov

Last modified: 02.05.2021


Silver has been part of active medical use for treatment and disinfection from ages, even in the present times. Particularly relevant today is the question of the effect of silver nanoparticles on bacteria and viruses, including against COVID-19. The study reviews distinct methods for producing silver nanoparticles. The comparison and preferences of different methods based on their classification and features are reviewed. The main goal of this study is to reveal the top-notch method and their benefits and prospects of the possibilities of the method - laser ablation, as a cost-effective and environment friendly technology for generating silver nanoparticles in an aqueous environment. The method of Pulsed Laser Ablation in Liquid for obtaining nanoparticles is explained in detail. The paper is divided into several main parts, starting with a briefing on silver and its nanoparticles and is followed by various methods for their production.



Silver Nanoparticles, Laser Ablation, Material Processing, Nanoparticles, Pulsed Laser Ablation in Liquid


J. W. Alexander, “History of the Medical Use of Silver,” SURGICAL INFECTIONS, vol. 10 (3), 2009. 

V. D. L. I. A. v. B. A. Graf Christina, “A General Method To Coat Colloidal Particles with Silica,” Langmuir, vol. 19 (17), pp. 6693–6700, 11 July 2003. 

K. H. M. S. Z. B. Iravani S, “ Synthesis of silver nanoparticles: chemical, physical and biological methods,” Research in Pharmaceutical Sciences, vol. 9, pp. 385–406, 2014. 

S. S., Biosynthesis and immobilization of nanoparticles and their applications, University of pune, 2005, pp. 1–57.

G. R. P. J. Pareek V., “Do physico-chemical properties of silver nanoparticles decide their interaction with biological media and bactericidal action? A review.,” Mater. Sci. Eng. C., vol. 90, pp. 739–749, 2018. 

Y. T. &. B. V. Shu Zhang, “A Review on Preparation and Applications of Silver-Containing Nanofibers,” Nanoscale Research Letters, vol. 80, 09 February 2016. 

H. F. K. a. M. H. Bernd Nowack, “120 Years of Nanosilver History: Implications for Policy Makers,” Environ. Sci. Technol., vol. 45(4), pp. 1177–1183, 10 January 2011. 

M. I. A. V. M. C. R. A. P. A. A. P. M. L. G. P. a. N. C. Maria Chiara Sportelli, “The Pros and Cons of the Use of Laser Ablation Synthesis for the Production of Silver Nano-Antimicrobials,” Antibiotics (Basel), vol. 7, 28 July 2018. 

B. B. B. C. R. e. Manish Kothakonda, “Core-Shell Nanoparticles for Energy Storage Applications,” in Pulsed Laser Ablation: Advances and Applications in Nanoparticles and Nanostructuring Thin Films, Pan Stanford Publishing Pte. Ltd., 2018, pp. 277-316.

M. P. B. V. S. e. Vardan Galstyan, “Metal Oxide Nanostructures in Food Applications: Quality Control and Packaging,” Chemosensors, vol. 6, no. 2, 14 April 2018. 

A. M.A.Virji, “8.06 - A Review of Engineered Nanomaterial Manufacturing Processes and Associated Exposures,” Comprehensive Materials Processing, vol. 8, pp. 103-125, 16 April 2014. 

L. G. C. E. M. e. Tomy Acsente, Tungsten Nanoparticles Produced by Magnetron Sputtering Gas Aggregation: Process Characterization and Particle Properties, London: IntechOpen, 2020. 

SPI LASERS LIMITED, [Online]. Available:

R. W. G. L. B. H. M. a. D. M. Getahun Merga, “Redox Catalysis on “Naked” Silver Nanoparticles,” J. Phys. Chem. C, vol. 111, pp. 12220–12226, 2007. 

U. D. Z. D. Z. A. Oliveira M, “ Influence of synthetic parameters on the size, structure, and stability of dodecanethiol-stabilized silver nanoparticles,” J Colloid Interface Sci., vol. 292, pp. 429–435, 2005. 

J. Y. Song and B. S. Kim, “Rapid biological synthesis of silver nanoparticles using plant leaf extracts,” Bioprocess and Biosystems Engineering, vol. 32, pp. 79-84, 26 04 2008. 

J. G. L. S.-Z. Qiao, “Chapter 21 - Synthetic Chemistry of Nanomaterials,” in Modern Inorganic Synthetic Chemistry (Second Edition), Elsevier B.V., 2017, pp. 613-640.

A. A. S. C. P. Suk Fun Chin, “Size Controlled Synthesis of Starch Nanoparticles by a Microemulsion Method,” Journal of Nanomaterials, vol. 2014. 

A. H. J. Z. Y. X. C. M. L. Yong X. Gan, “Hydrothermal Synthesis of Nanomaterials,” Journal of Nanomaterials, vol. 2020. 

S. B. S. A. R. Singaravelan, “Electrochemical synthesis, characterisation and phytogenic properties of silver nanoparticles,” Applied Nanoscience, vol. 5, no. 8, pp. 983–991, 18 January 2015. 

A. M. Hussein, Synthesis of silver nanoparticles, Mansoura University, 2016. 

S. Iravani, “Bacteria in Nanoparticle Synthesis: Current Status and Future Prospects,” vol. 2014. 

M. M. G. P. M. N. G. Palaniselvam Kuppusamy, “Biosynthesis of metallic nanoparticles using plant derivatives and their new avenues in pharmacological applications – An updated report,” Saudi Pharmaceutical Journal, vol. 24, no. 4, pp. 473-484, July 2016. 

R. d. L. Mariana Guilger-Casagrande, “Synthesis of Silver Nanoparticles Mediated by Fungi: A Review,” Bioeng. Biotechnol, vol. 7, 22 October 2019. 

S. V. M. A. e. Felix LewisOscar, Algal Nanoparticles: Synthesis and Biotechnological Potentials, London: IntechOpen, 2016. 

K. J. T. Y. K. T. S. H. Mafune F, “Structure and stability of silver nanoparticles in aqueous solution produced by laser ablation,” J Phys Chem B., vol. 104, pp. 8333–8337, 2000. 

S. A. V. V. S. G. B.-V. F. Dolgaev SI, “Nanoparticles produced by laser ablation of solids in liquid environment,” Appl Surf Sci., vol. 186, pp. 546–551, 2002. 

a. M. M. Amendola V., “Laser ablation synthesis in solution and size manipulation of noble metal nanoparticles,” Phys. Chem. Chem. Phys., vol. 11, pp. 3805–3821, 2009. 

F. M. a. M. T. Sakamoto M., “Light as a construction tool of metal nanoparticles: synthesis and mechanism,” j. Photochem. Photobiol. C, vol. 10, no. 1, pp. 33–56, 2009. 

N. N. Kawasaki M, “1064-nm laser fragmentation of thin Au and Ag flakes in acetone for highly productive pathway to stable metal nanoparticles,” Appl Surf Sci., vol. 253, pp. 2208–2216, 2006. 

B. C. N. B. E.-S. M. Link S, “Laser-Induced shape changes of colloidal gold nanorods using femtosecond and nanosecond laser pulses.,” J Phys Chem B., vol. 104, pp. 6152–6163, 2000. 

G. A. Shafeev, “FORMATION OF NANOPARTICLES UNDER LASER ABLATION OF SOLIDS IN LIQUIDS,” in Laser Ablation: Effects and Applications, New York, Nova Science Publishers, Inc., 2011, pp. 191-226.

I. I. B. N. N. N. I. K. K. D. B. K. G. B. A. A. S. Nikolov, “Influence of the laser pulse repetition rate and scanning speed on the morphology of Ag nanostructures fabricated by pulsed laser ablation of solid target in water,” Applied Physics : A Material science and processing, vol. 123, 27 October 2017. 

M. A. M. F. A. a. S. A. R. Amir Reza Sadrolhosseini, “Laser Ablation Technique for Synthesis of Metal Nanoparticle in Liquid,” in Laser Technology and its Applications, 2018. 

K. I. N. W. M. T. Takeshi Tsujia, “Preparation of silver nanoparticles by laser ablation in solution: influence of laser wavelength on particle size,” Applied Surface Science, Vols. 202 (1-2), pp. 80–85, December 2002. 

B. S. H. A. K. Mohammad Zamakhsari Alhami, “Synthesis of silver nanoparticles using laser ablation Method utilizing Nd:YAG Laser,” AIP Conference Proceedings, vol. 2202, no. 1, 27 December 2019. 

K. S. M. Y. e. Alexander Pyatenko, “Synthesis of silver nanoparticlesby laser ablation in pure water,” Applied Physics A, vol. 79, no. 4, pp. 803-806, September 2004. 

K. T. T. M. Tsuji T, “Preparation of nano-size particle of silver with femtosecond laser ablation in water.,” Applied Surface Science, vol. 206, pp. 314–320, 2003.